532 research outputs found

    The scale of sense : spatial extent and multimodal urban design

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    This paper is derived from the work of the UK AHRC/EPSRC 'Designing for the 21st Century' research project Multimodal Representation of Urban Space. This research group seeks to establish a new form of notation for urban design which pays attention to our entire sensory experience of place. This paper addresses one of the most important aspects of this endeavour: scale. Scale is of course a familiar abstraction to all architects and urban designers, allowing for representations tailored to different levels of detail and allowing drawings to be translated into build structures. Scale is also a factor in human experience: the spatial extent of each of our senses is different. Many forms of architectonic representation are founded upon the extension of the visual modality, and designs are accordingly tuned towards this sense. We can all speak from our own experience, however, that urban environments are a feast for all the senses. The visceral quality of walking down a wide tree-lined boulevard differs greatly from the subterranean crowds of the subway, or the meandering pause invited by the city square. Similarly, our experience of hearing and listening is more than just a passive observation by virtue of our own power of voice and the feedback created by our percussive movements across a surface or through a medium. Taste and smell are also excited by the urban environment, the social importance of food preparation and the associations between smell and public health are issues of sensory experience. The tactile experience of space, felt with the entire body as well as our more sensitive hands, allowing for direct manipulation and interactions as well as sensations of mass, heat, proximity and texture. Our project team shall present a series of tools for designers which explore the variety of sensory modalities and their associated scales. This suite of notations and analytical frameworks turn our attention to the sensory experience of places, and offers a method and pattern book for more holistic multi-sensory and multi-modal urban design

    Foot pain and foot health in an educated population of adults: results from the Glasgow Caledonian University Alumni Foot Health Survey

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    Abstract Background Foot pain is common amongst the general population and impacts negatively on physical function and quality of life. Associations between personal health characteristics, lifestyle/behaviour factors and foot pain have been studied; however, the role of wider determinants of health on foot pain have received relatively little attention. Objectives of this study are i) to describe foot pain and foot health characteristics in an educated population of adults; ii) to explore associations between moderate-to-severe foot pain and a variety of factors including gender, age, medical conditions/co-morbidity/multi-morbidity, key indicators of general health, foot pathologies, and social determinants of health; and iii) to evaluate associations between moderate-to-severe foot pain and foot function, foot health and health-related quality-of-life. Methods Between February and March 2018, Glasgow Caledonian University Alumni with a working email address were invited to participate in the cross-sectional electronic survey (anonymously) by email via the Glasgow Caledonian University Alumni Office. The survey was constructed using the REDCap secure web online survey application and sought information on presence/absence of moderate-to-severe foot pain, patient characteristics (age, body mass index, socioeconomic status, occupation class, comorbidities, and foot pathologies). Prevalence data were expressed as absolute frequencies and percentages. Multivariate logistic and linear regressions were undertaken to identify associations 1) between independent variables and moderate-to-severe foot pain, and 2) between moderate-to-severe foot pain and foot function, foot health and health-related quality of life. Results Of 50,228 invitations distributed, there were 7707 unique views and 593 valid completions (median age [inter-quartile range] 42 [31–52], 67.3% female) of the survey (7.7% response rate). The sample was comprised predominantly of white Scottish/British (89.4%) working age adults (95%), the majority of whom were overweight or obese (57.9%), and in either full-time or part-time employment (82.5%) as professionals (72.5%). Over two-thirds (68.5%) of the sample were classified in the highest 6 deciles (most affluent) of social deprivation. Moderate-to-severe foot pain affected 236/593 respondents (39.8%). High body mass index, presence of bunions, back pain, rheumatoid arthritis, hip pain and lower occupation class were included in the final multivariate model and all were significantly and independently associated with moderate-to-severe foot pain (p < 0.05), except for rheumatoid arthritis (p = 0.057). Moderate-to-severe foot pain was significantly and independently associated lower foot function, foot health and health-related quality of life scores following adjustment for age, gender and body mass index (p < 0.05). Conclusions Moderate-to-severe foot pain was highly prevalent in a university-educated population and was independently associated with female gender, high body mass index, bunions, back pain, hip pain and lower occupational class. Presence of moderate-to-severe foot pain was associated with worse scores for foot function, foot health and health-related quality-of-life. Education attainment does not appear to be protective against moderate-to-severe foot pain

    PH wave-front propagation in the urea-urease reaction

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    The urease-catalyzed hydrolysis of urea displays feedback that results in a switch from acid (pH ∌3) to base (pH ∌9) after a controllable period of time (from 10 to \u3e5000 s). Here we show that the spatially distributed reaction can support pH wave fronts propagating with a speed of the order of 0.1-1 mm min-1. The experimental results were reproduced qualitatively in reaction-diffusion simulations including a Michaelis-Menten expression for the urease reaction with a bell-shaped rate-pH dependence. However, this model fails to predict that at lower enzyme concentrations, the unstirred reaction does not always support fronts when the well-stirred reaction still rapidly switches to high pH. © 2012 by the Biophysical Society

    Masculinization of silver perch (bidyanus bidyanus mitchell 1838) by dietarysupplementation of 17 a-methyltestosterone

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    The aim of this research was to assess the possible use of dietary supplementation of 17a-methyltestosterone (MT), to produce all-male population of silver perch, Bidyanus bidyanus Mitchell 1838, as a step forward in producing neomales, which later can be used to produce an all-female population. Larvae were fed 17a-MT at various concentrations, viz. 0 (control), 9 and 18 mg/kg diet for the period of 30 days from 31 to 60 days post hatching (dph). Phenotypic sex ratios at 225 dph identified through histological examination revealed that MT significantly (P &lt; 0.05) increases the male percentage from 59% to 100%. Testes of MT-fed fish were well developed, had a normal appearance at the same developmental stages to that of the control group. No significant differences (P &gt; 0.05) in gonad weight (GW), gonad length (GL) and gonadosomatic index (GSI) among treatments which may indicate that the resulting neomales were viable. The MT supplementation did not influence the mortality rate, but significantly (P &lt; 0.05) increased the final weight and specific growth rate (SGR). The study suggests that the dietary supplementation of MT at 9–18 mg/kg of the diet from 31 to 60 dph larvae is effectively in inducing masculinization in silver perch

    After the peak water: the increasing influence of rock glaciers on alpine river systems

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    Human-accelerated climate change is quickly leading to glacier-free mountains, with consequences for the ecology and hydrology of alpine river systems. Water origin (i.e. glacier, snowmelt, precipitation, groundwater) is a key control on multiple facets of alpine stream ecosystems, since it drives the physico-chemical template of the habitat in which ecological communities reside and interact, and ecosystem processes occur. Accordingly, distinct alpine stream types and associated communities have been identified. However, unlike streams fed by glaciers (i.e. kryal), groundwater (i.e. krenal), and snowmelt-precipitation (i.e. rhithral), those fed by rock glaciers are still poorly documented. We characterized the physical and chemical features of these streams and investigated the influence of rock glaciers on the habitat template of alpine river networks. We analysed two subcatchments in a deglaciating area of the Central European Alps, where rock glacier-fed, groundwater-fed, and glacier-fed streams are all present. We monitored the spatial, seasonal, and diel variability of physical conditions (i.e. water temperature, turbidity, channel stability, discharge) and chemical variables (electrical conductivity, major ions and trace element concentrations) during the snowmelt, glacier ablation, and flow recession periods of two consecutive years. We observed distinct physical and chemical conditions and seasonal responses for the different stream types. Rock glacial streams were characterized by very low and constant water temperatures, stable channels, clear waters, and high concentrations of ions and trace elements that increased as summer progressed. Furthermore, one rock glacier strongly influenced the habitat template of downstream waters due to high solute export, especially in late summer under increased permafrost thaw. Given their unique set of environmental conditions, we suggest that streams fed by thawing rock glaciers are distinct river habitats that differ from those normally classified for alpine streams. Rock glaciers may become increasingly important in shaping the hydroecology of alpine river systems under continued deglaciation

    Resonant nonlinear magneto-optical effects in atoms

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    In this article, we review the history, current status, physical mechanisms, experimental methods, and applications of nonlinear magneto-optical effects in atomic vapors. We begin by describing the pioneering work of Macaluso and Corbino over a century ago on linear magneto-optical effects (in which the properties of the medium do not depend on the light power) in the vicinity of atomic resonances, and contrast these effects with various nonlinear magneto-optical phenomena that have been studied both theoretically and experimentally since the late 1960s. In recent years, the field of nonlinear magneto-optics has experienced a revival of interest that has led to a number of developments, including the observation of ultra-narrow (1-Hz) magneto-optical resonances, applications in sensitive magnetometry, nonlinear magneto-optical tomography, and the possibility of a search for parity- and time-reversal-invariance violation in atoms.Comment: 51 pages, 23 figures, to appear in Rev. Mod. Phys. in Oct. 2002, Figure added, typos corrected, text edited for clarit

    Search for displaced vertices arising from decays of new heavy particles in 7 TeV pp collisions at ATLAS

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    We present the results of a search for new, heavy particles that decay at a significant distance from their production point into a final state containing charged hadrons in association with a high-momentum muon. The search is conducted in a pp-collision data sample with a center-of-mass energy of 7 TeV and an integrated luminosity of 33 pb^-1 collected in 2010 by the ATLAS detector operating at the Large Hadron Collider. Production of such particles is expected in various scenarios of physics beyond the standard model. We observe no signal and place limits on the production cross-section of supersymmetric particles in an R-parity-violating scenario as a function of the neutralino lifetime. Limits are presented for different squark and neutralino masses, enabling extension of the limits to a variety of other models.Comment: 8 pages plus author list (20 pages total), 8 figures, 1 table, final version to appear in Physics Letters

    Measurement of the polarisation of W bosons produced with large transverse momentum in pp collisions at sqrt(s) = 7 TeV with the ATLAS experiment

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    This paper describes an analysis of the angular distribution of W->enu and W->munu decays, using data from pp collisions at sqrt(s) = 7 TeV recorded with the ATLAS detector at the LHC in 2010, corresponding to an integrated luminosity of about 35 pb^-1. Using the decay lepton transverse momentum and the missing transverse energy, the W decay angular distribution projected onto the transverse plane is obtained and analysed in terms of helicity fractions f0, fL and fR over two ranges of W transverse momentum (ptw): 35 < ptw < 50 GeV and ptw > 50 GeV. Good agreement is found with theoretical predictions. For ptw > 50 GeV, the values of f0 and fL-fR, averaged over charge and lepton flavour, are measured to be : f0 = 0.127 +/- 0.030 +/- 0.108 and fL-fR = 0.252 +/- 0.017 +/- 0.030, where the first uncertainties are statistical, and the second include all systematic effects.Comment: 19 pages plus author list (34 pages total), 9 figures, 11 tables, revised author list, matches European Journal of Physics C versio
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